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神經(jīng)生長，修復再生？突觸素（Synaptophysin）抗體的秘密 - 每日生物評論

神經(jīng)生長，修復再生？突觸素（Synaptophysin）抗體的秘密 - 每日生物評論

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首頁科研產(chǎn)品發(fā)現(xiàn)樣品檢測分析常見蛋白與IgG正文

神經(jīng)生長，修復再生？突觸素（Synaptophysin）抗體的秘密

分享按鈕?

突觸素(synaptophysin, SYP?)是一種與突觸功能密切相關的膜蛋白，Jahn于1885年首先從大鼠腦突觸囊泡中提取，因其相對分子質(zhì)量為38KDa，又稱為p38。它廣泛存在于機體所有神經(jīng)終末,特異性地分布于突觸前囊泡膜上.因其與神經(jīng)生長,修復再生和突觸重塑密切相關,成為近年來基礎醫(yī)學和康復醫(yī)學研究的熱點。

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據(jù)報道，突觸素（synaptophysin）出現(xiàn)在大腦、脊髓、視網(wǎng)膜的突觸前小泡，也出現(xiàn)在類似的腎上腺髓質(zhì)小泡以及神經(jīng)肌肉連接點。突觸素（synaptophysin）可能參與突觸囊泡的形成和胞吐。

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突觸素（synaptophysin）在神經(jīng)內(nèi)分泌腫瘤中廣泛表達，包括神經(jīng)母細胞瘤、神經(jīng)節(jié)神經(jīng)母細胞瘤、嗜鉻細胞瘤和非嗜鉻細胞副神經(jīng)節(jié)瘤。突觸素在上皮型神經(jīng)內(nèi)分泌腫瘤中也有表達，包括垂體腺瘤、胰島細胞瘤、甲狀腺髓樣癌、甲狀旁腺瘤、支氣管肺和胃腸道類癌、支氣管肺和胃腸道神經(jīng)內(nèi)分泌癌以及皮膚神經(jīng)內(nèi)分泌癌。

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研究靠得住，抗體第一步！作為專業(yè)的生命科學解決方案供應商，艾美捷為您推薦這個縱橫Nature, Cell的超能打的101組合成員：突觸素（synaptophysin）101 011，來自德國（SySy）

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產(chǎn)品貨號

101 011

產(chǎn)品名稱

Synaptophysin 1（抗體）

品牌

Synaptic Systems中國區(qū)總代理，艾美捷科技

應用類型

WB:?1 : 10000 (AP staining)

IP:?yes

ICC:?1 : 100 up to 1 : 1000

IHC:?1 : 500 up to 1 : 1000

IHC-P/FFPE:?1 : 500 up to 1 : 1000

EM:?yes

ELISA:?yes (see remarks)

反應種屬

人，小鼠，大鼠，哺乳動物

（與斑馬魚和其它脊椎動物有微弱反應）

抗原決定簇

大鼠突觸素1（Synaptophysin 1）的第219-307位氨基酸(UniProt Id:?P07825)

產(chǎn)品說明

50ug特異性抗體，凍干粉形式. 使用免疫原進行親和純化. 添加了白蛋白和疊氮化物以起到穩(wěn)定作用.

溶解建議

加入50ul無菌去離子水，獲得1mg/ml的PBS溶液.然后分裝保存與-20℃，直到使用。

說明書下載

點擊下載

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發(fā)表文章超160+：Nature, Cell，Science 課代表~

WB（78+）

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.

Cheret?C, Ganzella?M, Preobraschenski?J, Jahn?R, Ahnert-Hilger?G

Cell reports?(2021) 342: 108623.?101?011 WB; tested species: mouse

Cooperative function of synaptophysin and synapsin in the generation of?synaptic vesicle-like clusters in non-neuronal cells.

Park?D, Wu?Y, Lee?SE, Kim?G, Jeong?S, Milovanovic?D, Camilli?P, Chang?S

Nature communications?(2021) 121: 263.?101?011 WB, ICC; tested species: cos cells

Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.

Patzke?C, Brockmann?MM, Dai?J, Gan?KJ, Grauel?MK, Fenske?P, Liu?Y, Acuna?C, Rosenmund?C, Südhof?TC

Cell (2019) 1792: 498-513.e22.?101?011 WB, ICC; tested species: mouse

IP（6+）

Identification and characterization of the BRI2 interactome in the brain.

Martins?F, Marafona?AM, Pereira?CD, Müller?T, Loosse?C, Kolbe?K, da?Cruz?E?Silva?OAB, Rebelo?S

Scientific reports (2018) 81: 3548.?101?011 WB, IP; tested species: rat

ICC（42+）

Bassoon Controls Presynaptic Autophagy through Atg5.

Okerlund?ND, Schneider?K, Leal-Ortiz?S, Montenegro-Venegas?C, Kim?SA, Garner?LC, Waites?CL, Gundelfinger?ED, Reimer?RJ, Garner?CC

Neuron (2018) 973: 727.?101?011 ICC; tested species: mouse

Synaptic nanomodules underlie the organization and plasticity of spine synapses.

Hruska?M, Henderson?N, Le?Marchand?SJ, Jafri?H, Dalva?MB

Nature neuroscience?(2018) 215: 671-682.?101?011 ICC; tested species: rat

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

Jockusch?WJ, Speidel?D, Sigler?A, S?rensen?JB, Varoqueaux?F, Rhee?JS, Brose?N

Cell (2007) 1314: 796-808.?101?011 ICC

IHC（34+）

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen?T, Yan?X, Kononenko?NL, Ku?MC, Song?K, Ferrarese?L, Tarallo?V, Puchkov?D, Kochlamazashvili?G, Brachs?S, Varela?L, et al.

Nature neuroscience?(2017) 208: 1096-1103.?101?011 IHC; tested species: mouse

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.

Wilhelm?BG, Mandad?S, Truckenbrodt?S, Kr?hnert?K, Sch?fer?C, Rammner?B, Koo?SJ, Cla?en?GA, Krauss?M, Haucke?V, Urlaub?H, et al.

Science (New York, N.Y.) (2014) 3446187: 1023-8.?101?011 WB, ICC, IHC; tested species: mouse,rat

EM（1+）

Synaptic membrane proteins form stable microdomains in early endosomes.

Geumann?U, Sch?fer?C, Riedel?D, Jahn?R, Rizzoli?SO

Microscopy research and technique (2010) 736: 606-17.?101?011 ICC, EM

ELISA（1+）

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission.

Vasileva?M, Horstmann?H, Geumann?C, Gitler?D, Kuner?T

The European journal of neuroscience (2012) 368: 3005-20.?101?011 ELISA

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部分結果圖展示：

WB

ICC

IHC

IHC-P

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運輸條件

所有抗體和對照蛋白/肽以凍干粉狀態(tài)（真空冷凍干燥）運輸，室溫下可以在數(shù)周內(nèi)保持穩(wěn)定和活性。

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收到產(chǎn)品之后的操作和樣品瓶的儲存

無標記和生物素標記抗體以及對照蛋白在重懸前應保存在 4°C 的條件下。 在凍干狀態(tài)下不要存放在冷凍柜里！低于零攝氏度會導致反應性降低。

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重懸

所有抗體均由PBS凍干。用PBS溶解抗體凍干粉，請參照數(shù)據(jù)手冊定量添加去離子水。大容量溶解時，先添加去離子水，然后適量的PBS和蛋白穩(wěn)定劑（例如BSA）至2%的最終濃度。添加蛋白穩(wěn)定劑時請注意，部分抗體已經(jīng)含有血清白蛋白。制作重懸溶液時請小心打開蓋子。添加去離子水后，輕微晃動溶液。為使液體聚集在樣品瓶底部，可以使用離心機離心。操作離心機時，可以在50ml離心管中樣品瓶下面鋪墊廢紙，以方便離心后取出。

為抑制細菌生長，可以添加少量的疊氮化物或硫柳汞作為防腐劑。該操作特別適用于分量包裝在4°C條件下保存。可以向不帶標記的一抗添加甘油，以避免凍融循環(huán)。

................................................................................................

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發(fā)布日期：2021年05月07日??所屬分類：常見蛋白與IgG

標簽：SynaptophysinSYP突觸體素突觸素突觸素抗體

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轉(zhuǎn)載請注明：神經(jīng)生長，修復再生？突觸素（Synaptophysin）抗體的秘密 - 每日生物評論 +復制鏈接

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突觸素（Synaptophysin）抗體

2021-04-27 10:21 ? 點擊次數(shù)： 關鍵詞： 突觸素 突觸體素 突觸素抗體 Synaptophysin,SYP

突觸素(synaptophysin, SYP )是一種與突觸功能密切相關的膜蛋白，Jahn于1885年首先從大鼠腦突觸囊泡中提取，因其相對分子質(zhì)量為38KDa，又稱為p38。它廣泛存在于機體所有神經(jīng)終末,特異性地分布于突觸前囊泡膜上.因其與神經(jīng)生長,修復再生和突觸重塑密切相關,成為近年來基礎醫(yī)學和康復醫(yī)學研究的熱點。??據(jù)報道，突觸素（synaptophysin）出現(xiàn)在大腦、脊髓、視網(wǎng)膜的突觸前小泡，也出現(xiàn)在類似的腎上腺髓質(zhì)小泡以及神經(jīng)肌肉連接點。突觸素（synaptophysin）可能參與突觸囊泡的形成和胞吐。?突觸素（synaptophysin）在神經(jīng)內(nèi)分泌腫瘤中廣泛表達，包括神經(jīng)母細胞瘤、神經(jīng)節(jié)神經(jīng)母細胞瘤、嗜鉻細胞瘤和非嗜鉻細胞副神經(jīng)節(jié)瘤。突觸素在上皮型神經(jīng)內(nèi)分泌腫瘤中也有表達，包括垂體腺瘤、胰島細胞瘤、甲狀腺髓樣癌、甲狀旁腺瘤、支氣管肺和胃腸道類癌、支氣管肺和胃腸道神經(jīng)內(nèi)分泌癌以及皮膚神經(jīng)內(nèi)分泌癌。?研究靠得住，抗體第一步！作為專業(yè)的生命科學解決方案供應商，艾美捷為您推薦這個縱橫Nature, Cell的超能打的101組合成員：突觸素（synaptophysin）101 011，來自德國（SySy）??

產(chǎn)品貨號

101 011

產(chǎn)品名稱

Synaptophysin 1（抗體）

品牌

Synaptic Systems中國區(qū)總代理，艾美捷科技

應用類型

WB: 1 : 10000 (AP staining) IP: yes ICC: 1 : 100 up to 1 : 1000 IHC: 1 : 500 up to 1 : 1000 IHC-P/FFPE: 1 : 500 up to 1 : 1000 EM: yes ELISA: yes (see remarks)

反應種屬

人，小鼠，大鼠，哺乳動物 （與斑馬魚和其它脊椎動物有微弱反應）

抗原決定簇

大鼠突觸素1（Synaptophysin 1）的第219-307位氨基酸(UniProt Id: P07825)

產(chǎn)品說明

50ug特異性抗體，凍干粉形式. 使用免疫原進行親和純化. 添加了白蛋白和疊氮化物以起到穩(wěn)定作用.

溶解建議

加入50ul無菌去離子水，獲得1mg/ml的PBS溶液.然后分裝保存與-20℃，直到使用。

說明書下載

點擊下載

?發(fā)表文章超160+：Nature, Cell，Science 課代表~

WB（78+）

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels. Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G Cell reports (2021) 342: 108623. 101 011 WB; tested species: mouse Cooperative function of synaptophysin and synapsin in the generation of?synaptic vesicle-like clusters in non-neuronal cells. Park D, Wu Y, Lee SE, Kim G, Jeong S, Milovanovic D, Camilli P, Chang S Nature communications (2021) 121: 263. 101 011 WB, ICC; tested species: cos cells Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Patzke C, Brockmann MM, Dai J, Gan KJ, Grauel MK, Fenske P, Liu Y, Acuna C, Rosenmund C, Südhof TC Cell (2019) 1792: 498-513.e22. 101 011 WB, ICC; tested species: mouse

IP（6+）

Identification and characterization of the BRI2 interactome in the brain. Martins F, Marafona AM, Pereira CD, Müller T, Loosse C, Kolbe K, da Cruz E Silva OAB, Rebelo S Scientific reports (2018) 81: 3548. 101 011 WB, IP; tested species: rat

ICC（42+）

Bassoon Controls Presynaptic Autophagy through Atg5. Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC Neuron (2018) 973: 727. 101 011 ICC; tested species: mouse Synaptic nanomodules underlie the organization and plasticity of spine synapses. Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB Nature neuroscience (2018) 215: 671-682. 101 011 ICC; tested species: rat CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Jockusch WJ, Speidel D, Sigler A, S?rensen JB, Varoqueaux F, Rhee JS, Brose N Cell (2007) 1314: 796-808. 101 011 ICC

IHC（34+）

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, et al. Nature neuroscience (2017) 208: 1096-1103. 101 011 IHC; tested species: mouse Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, Mandad S, Truckenbrodt S, Kr?hnert K, Sch?fer C, Rammner B, Koo SJ, Cla?en GA, Krauss M, Haucke V, Urlaub H, et al. Science (New York, N.Y.) (2014) 3446187: 1023-8. 101 011 WB, ICC, IHC; tested species: mouse,rat

EM（1+）

Synaptic membrane proteins form stable microdomains in early endosomes. Geumann U, Sch?fer C, Riedel D, Jahn R, Rizzoli SO Microscopy research and technique (2010) 736: 606-17. 101 011 ICC, EM

ELISA（1+）

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission. Vasileva M, Horstmann H, Geumann C, Gitler D, Kuner T The European journal of neuroscience (2012) 368: 3005-20. 101 011 ELISA

?部分結果圖展示：

WB

ICC

IHC

IHC-P

?運輸條件 所有抗體和對照蛋白/肽以凍干粉狀態(tài)（真空冷凍干燥）運輸，室溫下可以在數(shù)周內(nèi)保持穩(wěn)定和活性。?收到產(chǎn)品之后的操作和樣品瓶的儲存 無標記和生物素標記抗體以及對照蛋白在重懸前應保存在 4°C 的條件下。 在凍干狀態(tài)下不要存放在冷凍柜里！低于零攝氏度會導致反應性降低。?重懸所有抗體均由PBS凍干。用PBS溶解抗體凍干粉，請參照數(shù)據(jù)手冊定量添加去離子水。大容量溶解時，先添加去離子水，然后適量的PBS和蛋白穩(wěn)定劑（例如BSA）至2%的最終濃度。添加蛋白穩(wěn)定劑時請注意，部分抗體已經(jīng)含有血清白蛋白。制作重懸溶液時請小心打開蓋子。添加去離子水后，輕微晃動溶液。為使液體聚集在樣品瓶底部，可以使用離心機離心。操作離心機時，可以在50ml離心管中樣品瓶下面鋪墊廢紙，以方便離心后取出。為抑制細菌生長，可以添加少量的疊氮化物或硫柳汞作為防腐劑。該操作特別適用于分量包裝在4°C條件下保存?？梢韵虿粠擞浀囊豢固砑痈视?，以避免凍融循環(huán)。................................................................................................看到這兒，您心動了嗎？馬上聯(lián)系小艾吧！或者掃描下方二維碼，即可聯(lián)系您的專屬客服哦~??作為一家具有高端的技術實力、先進的經(jīng)營管理水平和完善的市場銷售體系的生物高科技企業(yè)，總部位于武漢光谷高新技術開發(fā)區(qū)，服務面向全國。艾美捷科技是集進口試劑、實驗室耗材銷售、技術服務與合約開發(fā)為一體的專業(yè)化高科技公司，為用戶提供專業(yè)的前沿資訊、完備的產(chǎn)品、整合的解決方案，及優(yōu)質(zhì)的物流服務。?艾美捷科技與國內(nèi)外優(yōu)秀的生物試劑供應商優(yōu)保持著密切的合作關系，目前已成為眾多國際知名品牌的中國總代理或一級代理，主要包括：AmyJet、AmyJet、AAT Bioquest、Abbexa、Abnova、Agrisera、Anogen、Biosensis、Biovision、Caisson Labs、Cell Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、Hycult Biotech、ImmunoReagents、Jackson、LifeSensors、LigaTrap、Mabtech、Matreya、Norgen Biotek、Origene、ProImmune、ProSpec、ScyTek、Solis BioDyne、SouthernBiotech、StressMarq、SySy、US Biological、TRC等，可以在短時間內(nèi)為用戶提供專業(yè)的前沿資訊、完備的產(chǎn)品及物流服務。??

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不忘初心四十載 砥礪奮進新征程——慶祝耀皮玻璃集團成立40周年先進表彰會隆重召開

2月2日下午，集團總部一樓多功能廳張燈結彩，人聲鼎沸，以“不忘初心四十載 砥礪奮進新征程”為主題的慶祝耀皮玻璃集團成立40周年先進表彰會在這里隆重召開。集團黨政班子成員、先進代表、員工代表等80余人參加了此次會議。各子公司以線上視頻直播的方式參會。

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2024-01-30

聚焦綠色建筑，攜手共創(chuàng)未來——耀皮新疆推廣交流會圓滿落幕

2024年1月24日-25日，為了更好地實現(xiàn)三方聯(lián)動助力銷售開拓市場，由研究院、市場部和重慶工玻三方組成的耀皮銷售技術專業(yè)服務團隊來到了新疆，先后在新疆建筑設計院、新疆維泰開發(fā)建設（集團）股份有限公司開展產(chǎn)品推廣交流會。

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2024-01-12

新年新氣象，奮力新征程

為助推耀皮玻璃集團各項工作開好局、起好步，實現(xiàn)高質(zhì)量發(fā)展，集團各部門、子公司正以奮發(fā)有為的精神狀態(tài)和只爭朝夕的奮斗姿態(tài)，投入到節(jié)后的各項工作中，開足馬力忙生產(chǎn)，奮力跑出高質(zhì)量發(fā)展“加速度”！

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上海耀皮玻璃集團股份有限公司

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Shanghai Yaohua Pilkington Glass Group Co.,Ltd. (Abbr: SYP) was founded in November 1983. It became one of the first public listed glass manufacturers in China with its IPO completed in 1993.

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1983

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Shanghai Yaohua Pilkington Glass Co., Ltd was founded, which was one of the earliest joint venture companies at that time.

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Float Glass

Architectural Processing Glass

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Float Glass

LOW IRON FLOAT GLASS

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SINGLE CURVED TEMPERED GLASS

SYP MARBLE GLASS

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Shanghai Yaohua Pilkington Glass Group Co.,Ltd. (Abbr: SYP) was founded in November 1983.It became one of the first public listed glass manufacturers in China with its IPO completed in1993.Currently SYP has three major Businesses , float glass, architectural processed glass and autoglass, with total assets over RMB 7.3 billion. SYP can produce 680,000 tons float glass, 50million square meters architectural processed glass and 4 million sets of autoglass annually.SYP has long been certified with ISO9001: 2000 quality management system and the ISO14001international certificate of SGS in China. Moreover, SYP was awarded Shanghai Famous Trademark at the end of 2005. The float glass and IGU products were awarded the China Top Brandproducts.SYP architectural processed glass products have been awarded Shanghai Top 100 Brand Name products for consecutive eight years.While maintaining a leading position in China’s glass industry, SYP is striving to establish itself as a leading multinational glass manufacturer.

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1983

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Shanghai Yaohua Pilkington Glass Co., Ltd was founded, which was one of the earliest joint venture companies at that time.

1987

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After importing “Float glass process” of Pilkington UK, SYP first float glass line with 180,000 tons’ annual capacity was built. It became a company which can produce all kinds of high quality clear float glass.

1993

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It became one of the first public listed glass manufactures in China after restructuring and listing.

1995

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The second tinted float glass line was built with 90.000 tons’ annual capacity, which ended the condition in China that tinted float glass was fully depended on import.

1997

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Shanghai Yaohua Pilkington Glass Co., Ltd Kangqiao glass processing base went into operation.

2000

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Shanghai Glass and Glass Processing R&D center was established in SYP.SYP bought “Shanghai FuHua Glass Co., Ltd”, which Ford of American invested in China and renamed it to “SYP Kangqiao Autoglass Co., Ltd.”SYP bought “Guangdong float glass Co., ltd”, which PPG of American invested in China and renamed it to “Guangdong SYP Glass Co., Ltd.”

2003

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SYP bought “Tianjin NSG float glass Co., Ltd”, which NSG of Japanese invested in China and renamed it to “Tianjin SYP Glass Co., ltd”

2004

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“Shanghai SYP Engineering Glass Co., ltd” went into production.

2006

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“Jiangsu Pilkington SYP Glass Co., Ltd.” went into production.“Changshu SYP Special Glass Co., Ltd. “went into production.SYP brand float glass, Low E coated glass, tempered glass, Insulated glass were regarded as ”State Inspection exemption product” by General Administration of Quality Supervision, Inspection and Quarantine of the PRC.

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手把手教你基因進化樹的構建（一） - 知乎

手把手教你基因進化樹的構建（一） - 知乎切換模式寫文章登錄/注冊手把手教你基因進化樹的構建（一）生信果對于基因進化樹的構建，大家應該都很苦惱吧。最近小果剛好需要構建進化樹，在經(jīng)過學習之后，也掌握了如何建樹。那么現(xiàn)在就讓小果來帶大家一步步從序列數(shù)據(jù)的下載，再到基因進化樹的建立，詳細地手把手教學吧！一、蛋白質(zhì)序列數(shù)據(jù)的下載在這里我們將在NCBI數(shù)據(jù)庫中，搜尋Syp synaptophysin蛋白質(zhì)的fastq序列作為數(shù)據(jù)準備。其中Synaptophysin（SYP）是一種神經(jīng)元內(nèi)高度保守的膜蛋白，它主要存在于突觸小泡膜上，并參與突觸傳遞和神經(jīng)遞質(zhì)釋放的過程。它被廣泛用作神經(jīng)末梢和神經(jīng)內(nèi)分泌腫瘤的免疫組化標記物，可以用于幫助鑒定和分類這些腫瘤。因此，在病理學和臨床診斷中，鑒定SYP的表達水平可以提供有用的信息，對于診斷和治療策略的制定具有重要意義。如圖所示，在選擇了Protein之后，我們在NCBI的搜索框中搜尋Syp synaptophysin的界面如下：二、搜尋檢索的處理因為在搜尋的過程中，搜尋的結果太多，為了能夠進一步的篩查數(shù)據(jù)，我們可以在搜尋欄中增添邏輯運算符，如NOT、OR、AND等。如圖所示，我們?yōu)榱诉M一步地去除標題中包含hypothetical的數(shù)據(jù)，將在檢索框中，輸入Syp synaptophysin NOT hypothetical[title] ，然后需要注意的是，我們在后面需要備注[title] 與此同時，我們也可以在Search details中復制搜索的結果并保存，在日后需要再次搜尋同樣的結果的時候，可以直接復制上去緊接著，我們點擊Send to按鈕，對已經(jīng)選取不同物種的蛋白質(zhì)序列進行下載，在這里我們選取十種左右不同的物種的SYP蛋白序列。選擇FASTA的格式，點擊Create File按鈕，將下載到sequence.fasta的文件中三、下載序列的處理為了進一步地使得后面構建的進化樹中，能夠很好地觀察到物種名，我們在這里需要對>后面的id和物種名進行處理，將id名替換成為物種名所以在此我們將使用正則表達式進行替換，如圖所示為替換的方式，其中的Find what中的字符為>([^ ]+).*\[(.*)\]>([^ ]+).*\[(.*)\]的意思是：匹配以大于符號（>）開頭，之后是一個或多個非空格字符的字符串，然后是一個方括號（[]）括起來的任意字符。而當使用\2時，它表示對第二個捕獲組的引用。這意味著，如果正則表達式中的模式匹配了一個字符串，并且第二個捕獲組捕獲了一些內(nèi)容，那么\2將被替換為該捕獲組中所捕獲的內(nèi)容。例如，如果應用正則表達式>([^ ]+).*\[(.*)\]于字符串>Hello [World]，那么\2將被替換為World，因為World是第二個捕獲組所捕獲的內(nèi)容。所得的結果如下：好啦，對于已經(jīng)下載好的蛋白質(zhì)序列也處理了，我們接下來就可以進行基因進化樹的構建了！在下一篇中，小果將給大家?guī)砀敿毜?，去使用mega軟件進行進化樹的構建的過程！是不是非常期待呢？發(fā)布于 2023-10-17 11:10?IP 屬地上?；蛏欧治?贊同 2??1 條評論?分享?喜歡?收藏?申請

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耀皮玻璃_百度百科

_百度百科 網(wǎng)頁新聞貼吧知道網(wǎng)盤圖片視頻地圖文庫資訊采購百科百度首頁登錄注冊進入詞條全站搜索幫助首頁秒懂百科特色百科知識專題加入百科百科團隊權威合作下載百科APP個人中心收藏查看我的收藏0有用+10耀皮玻璃播報討論上傳視頻上海耀華皮爾金頓玻璃股份有限公司上海耀華皮爾金頓玻璃股份有限公司前身上海耀華皮爾金頓玻璃公司，1983年6月7日由中國建材技術裝備總公司，上海耀華玻璃廠，中行上海信托咨詢公司，皮爾金頓國際控股公司BV和以色列聯(lián)合發(fā)展公司（香港）共同投資成立。公司名稱上海耀華皮爾金頓玻璃股份有限公司外文名Shanghai Yaohua Pilkington Glass Co., Ltd.總部地點上海市浦東新區(qū)濟陽路100號經(jīng)營范圍非金屬礦物制品業(yè)證券代碼600819證券簡稱耀皮玻璃注冊資本73125.008萬元工商登記號企股滬總字第019022號上市時間1994年01月28日目錄1公司發(fā)展2服務宗旨3企業(yè)榮譽4分支機構?天津?廣東?江蘇?常熟?上海耀皮?上海耀皮?天津?耀皮汽車?耀皮公司5證券資料6投資亮點7十大股東8最大股東易主公司發(fā)展播報編輯耀皮玻璃上海耀華皮爾金頓玻璃股份有限公司（中文簡稱“耀皮玻璃”，英文簡稱“SYP”）成立于1983年，是當時國內(nèi)最大的中英合資企業(yè)，1993年改制上市，總部位于上海市浦東新區(qū)濟陽路100號。公司擁有市級企業(yè)技術中心及國內(nèi)一流水平的檢測中心，主要業(yè)務覆蓋浮法玻璃、建筑加工玻璃和汽車玻璃三大領域。截至2006年底，公司總資產(chǎn)超過46億元，銷售收入突破17億元。在浮法玻璃領域，公司不斷發(fā)展壯大。2000年和2003年，公司先后收購了廣東浮法玻璃有限公司（現(xiàn)更名為廣東耀皮玻璃有限公司）和天津日板浮法玻璃有限公司（現(xiàn)更名為天津耀皮玻璃有限公司）。2005年，公司與皮爾金頓合資成立江蘇皮爾金頓耀皮玻璃有限公司，與格拉斯林有限公司合資成立常熟耀皮特種玻璃有限公司。如今公司已擁有采用英國Pilkington技術、美國PPG技術和日本板硝子（NSG）技術的優(yōu)質(zhì)浮法玻璃生產(chǎn)線。浮法玻璃業(yè)務下屬上海濟陽工廠、廣東耀皮玻璃有限公司、天津耀皮玻璃有限公司、江蘇皮爾金頓玻璃有限公司共五條生產(chǎn)線。主要產(chǎn)品有：1.8mm-25mm優(yōu)質(zhì)透明浮法玻璃、2mm-12mm優(yōu)質(zhì)F綠、H綠、藍、灰、黑本體著色浮法玻璃。另有涉足太陽能電池領域的超白壓延玻璃生產(chǎn)線一條，是公司在節(jié)能、環(huán)保領域的新突破。公司是國內(nèi)商用建筑玻璃的優(yōu)秀供應商。1995年，公司參股上海陽光鍍膜玻璃有限公司，并受托進行管理。之后，公司先后斥資近7億元在上?？禈蚬I(yè)園區(qū)建成了綜合性建筑玻璃加工基地。2002年公司對上海陽光鍍膜玻璃有限公司全面控股。2012年，公司在上海和京津兩地擁有四家工廠，數(shù)十條玻璃深加工生產(chǎn)線，是國內(nèi)加工玻璃行業(yè)規(guī)模最大、設備最先進、綜合配套能力最強的玻璃深加工企業(yè)之一。主要產(chǎn)品有：鍍膜、中空、夾層、鋼化、彩釉、熱彎、家具等各種安全、環(huán)保、節(jié)能、裝飾系列加工玻璃。耀皮玻璃2000年，公司收購了上海福華汽車玻璃有限公司（現(xiàn)更名為上海耀皮汽車玻璃有限公司），開始涉足汽車玻璃領域。2004年底，年產(chǎn)80萬套的汽車玻璃新廠在康橋工業(yè)園區(qū)建成投產(chǎn)。公司引進英國皮爾金頓汽車玻璃成套加工技術和設備，主營各類汽車用前擋印刷曲面夾層玻璃，汽車用單曲面鋼化玻璃，熱線印刷玻璃及各類汽車玻璃總成。產(chǎn)品的產(chǎn)量、質(zhì)量和市場占有率均在同行中名列前茅。公司自投產(chǎn)以來，堅持走市場、質(zhì)量、效益型的發(fā)展道路，在市場經(jīng)濟大潮中頑強拚搏、艱苦創(chuàng)業(yè)，企業(yè)規(guī)模不斷擴大，管理水平不斷提高。1994年3月，耀皮玻璃在中國玻璃行業(yè)第一個建立了經(jīng)國際權威機構認證的ISO9002質(zhì)量體系；2000年7月，公司又率先通過了ISO14001環(huán)境管理體系國際認證。2012年，公司產(chǎn)品分別通過3C、澳標、美國、英國等國際認證，并形成了較強的新產(chǎn)品獨立開發(fā)能力。公司已申請和獲得了10多項發(fā)明專利，多次獲得各級各類新品開發(fā)殊榮。耀皮商標是上海市著名商標，中國名牌產(chǎn)品，國家免檢產(chǎn)品。多年的努力使公司的生產(chǎn)效率和經(jīng)濟效益在同行業(yè)一直保持較高水平，公司曾三次被評為全國十佳合資企業(yè)，自1989年以來被連續(xù)評為全國外商投資創(chuàng)匯創(chuàng)利雙優(yōu)企業(yè)。比贏利的增長和獲得的榮譽更為重要的是，公司在實踐中培養(yǎng)了一批高素質(zhì)的員工隊伍，形成了勇于開拓的作風?！坝肋h有新的追求”是公司的理念。自成立以來，公司從未滿足于過去的成績，從未駐足不前、等待觀望，而是沿著既定的目標不斷向前發(fā)展，力求將公司建成積極進取，中國聲譽最佳、實力最強的玻璃制造與深加工企業(yè)，并為早日躋身國際一流企業(yè)而不懈奮斗！服務宗旨播報編輯耀皮玻璃1、“以客為尊”：不管發(fā)生什么情況，我們都要努力善待顧客。2、耐心對待每一位顧客，對待顧客的熱情不能因某些顧客的不友好態(tài)度而打折扣。3、平等對待每一位顧客，不要責備或訓斥顧客，也不要讓他們感到在你眼中無關緊要。4、以友好的態(tài)度給顧客提供幫助和建議，讓他（她）感覺到受歡迎和受尊重。5、以滿足顧客的需要為己任。6、不自作主張地處理顧客的問題和抱怨。7、在沒有把問題弄清楚之前，不要把顧客及其需求推給同事。8、努力獲得顧客的反饋意見，不管它是肯定或否定，并分析原因和提出改進措施。企業(yè)榮譽播報編輯中國名牌產(chǎn)品公司自1986年起已經(jīng)6次被評為外商投資先進技術型企業(yè)國家免檢產(chǎn)品產(chǎn)品質(zhì)量免檢證書公司自2001年起連續(xù)被評為高新技術企業(yè)公司自1996年起連續(xù)10年被評為外商投資雙優(yōu)企業(yè)上海市知識產(chǎn)權示范企業(yè)上海市著名商標證書自1990年起連續(xù)16年被評為上海市文明單位自1999年起已經(jīng)6次被評為上海名牌產(chǎn)品守合同重信用企業(yè)合同信用等級認定證書分支機構播報編輯天津天津耀皮玻璃有限公司（原中日合資企業(yè)天津日板浮法玻璃有限公司）成立于1995年4月，占地面積31公頃，位于天津濱海新區(qū)大港區(qū)北圍堤路煉油廠西側(cè)，距離天津市中心40km，塘沽港30km，交通十分便利。廠內(nèi)有鐵路專用線，便于原料、燃料和產(chǎn)品的運輸。廣東廣東耀皮玻璃有限公司（簡稱廣東耀皮或GSYP）原名廣東浮法玻璃有限公司，于1984年由招商局輪船股份有限公司、中國北方工業(yè)公司深圳分公司、廣東國際信托投資公司、深圳市建筑材料工業(yè)公司四家股東組成的南方玻璃有限公司與由美國PPG國際工業(yè)公司、泰國鄭亮蔭投資公司組成的香港泛華亞有限公司簽約成立，于1987年7月建成投產(chǎn)。公司坐落于深圳經(jīng)濟特區(qū)蛇口工業(yè)區(qū)，占地約13公頃。江蘇江蘇皮爾金頓耀皮玻璃有限公司(JSYP)由上海耀華皮爾金頓玻璃股份有限公司（中方）與英國皮爾金頓有限公司（外方）合資組建。公司投資總額為9668萬美元，其中注冊資本為4833萬美元。江蘇皮爾金頓耀皮玻璃有限公司位于江蘇省常熟經(jīng)濟開發(fā)區(qū)，總占地面積約877畝。北枕長江，緊鄰國家一類開放口岸--常熟港，距上海耀皮玻璃總部約130公里，西接在建的蘇通大橋，沿江高速穿境而過，水陸交通便利。常熟常熟耀皮特種玻璃有限公司(簡稱“常熟耀皮”或“CSYP”)位于江蘇省常熟經(jīng)濟開發(fā)區(qū)，一期工程占地面積約80畝。常熟耀皮特種玻璃有限公司北枕長江，緊鄰國家一類開放口岸--常熟港，距上海130公里，西接蘇通大橋，沿江高速穿境而過，水陸交通便利，水、電、氣等配套設施完善。公司由上海耀華皮爾金頓玻璃股份有限公司（SYP）與香港格拉斯林有限公司合資組建，投資總額2500萬美元。上海耀皮上海耀皮建筑玻璃有限公司是上海耀華皮爾金頓玻璃股份有限公司的控股子公司，其日常經(jīng)營由上海耀華皮爾金頓玻璃股份有限公司加工玻璃事業(yè)部負責。公司前身上海陽光鍍膜玻璃有限公司，成立于1992年7月，主營生產(chǎn)和銷售鍍膜玻璃、鋼化玻璃、中空玻璃及其系列深加工產(chǎn)品。公司的投資方包括上海耀華皮爾金頓玻璃股份有限公司、上海建筑材料（集團）總公司、北京中北窯業(yè)技術公司等組成。上海耀皮上海耀皮工程玻璃有限公司是一家中外合資企業(yè)，成立于2002年10月，主要生產(chǎn)和銷售鋼化玻璃、鍍膜玻璃、中空玻璃及其系列深加工產(chǎn)品。公司的投資方由上海耀皮建筑玻璃有限公司、香港格拉斯林有限公司組成，公司日常經(jīng)營由上海耀華皮爾金頓玻璃股份有限公司加工玻璃事業(yè)部負責。天津天津耀皮工程玻璃有限公司是一家中外合資企業(yè)，成立于2006年12月，主營生產(chǎn)和銷售鋼化玻璃、鍍膜玻璃、中空玻璃及其系列深加工產(chǎn)品，并提供產(chǎn)品的售后技術服務。公司的投資方由上海耀皮建筑玻璃有限公司、格拉斯林有限公司組成，公司的日常經(jīng)營管理由上海耀華皮爾金頓玻璃股份有限公司加工玻璃事業(yè)部負責。耀皮汽車上海耀皮汽車玻璃有限公司（簡稱“耀皮康橋汽?！被蛘摺癝YPKA”）的前身為上海福華玻璃有限公司，1994年7月成上海耀皮汽車玻璃有限公司立，投資方為美國福特公司和上海建筑材料（集團）總公司。2004年公司成為由上海耀華皮爾金頓玻璃股份有限公司（簡稱“耀皮玻璃”或者“SYP”）、上海建筑材料（集團）總公司兩方的合資企業(yè)，并更名為“上海耀皮汽車玻璃有限公司”。耀皮公司上海耀皮康橋汽車玻璃有限公司是一家專業(yè)從事OEM汽車玻璃及玻璃總成研發(fā)、制造與銷售的中外合資企業(yè)，公司提供各類汽車前風擋、車門、側(cè)窗、后風擋玻璃，2012年被評為“上海市外商投資先進技術企業(yè)”。公司引進了世界上最先進的汽車玻璃設計和制造技術，并進行消化吸收和自主創(chuàng)新。自主開發(fā)的半鋼化夾層車門玻璃，可吸收紫外線99%，抗沖擊力較普通玻璃提高了20倍，降低了6分貝風噪音，率先為國產(chǎn)高檔轎車提供了高級隔音夾層汽車安全玻璃。證券資料播報編輯耀皮玻璃證券簡稱 耀皮玻璃證券類型A股曾用名 G耀皮上市狀態(tài) 已經(jīng)上市上市國家/地區(qū) 中國大陸上市交易所上海證券交易所上市日期 1994-01-28發(fā)行價(元) 6.8上市首日收盤價(元) 14.7上市首日漲跌幅(%) 116.18上市首日換手率(%) 19.22主承銷商： 上海萬國證券公司上市推薦人： 上海萬國證券公司審計機構： 上海上會會計師事務所有限公司經(jīng)辦會計師： 張文枝 巢旭投資亮點播報編輯1. 公司是國內(nèi)商用建筑玻璃的優(yōu)秀供應商。年產(chǎn)80萬套的汽車玻璃新廠已在康橋工業(yè)園區(qū)建成投產(chǎn),成為上海通用、上海大眾、東風悅達起亞、南京依維柯、福建東南等國內(nèi)諸多汽車廠家的合格供應商并批量供貨。2. 公司2009年前三季度主要財務指標:每股收益-0.1340(元),每股凈資產(chǎn)2.6400(元),凈資產(chǎn)收益率-5.0840%,營業(yè)收入1696352409.4700(元),同比增減-13.8470%;歸屬上市公司股東的凈利潤-98059236.11(元),同比增減-336.9926%。3. 公司可用于投資理財?shù)南揞~為人民幣5億元，其中用于專戶理財?shù)南揞~不超過人民幣2億元,其余部分可用于購買新股或由金融機構經(jīng)批準發(fā)行的低風險理財產(chǎn)品,上述投資理財?shù)钠谙拗?010年6月止。4. 截止2009年5月6日,東方資產(chǎn)累計減持公司無限售條件流通股7182850股(占公司總股本的0.98%),尚持有公司無限售條件流通股36305498股(占公司總股本的4.96%)。5. 控股子公司廣東耀皮玻璃有限公司由于熔窯臨近大修且產(chǎn)品結構不夠合理,且經(jīng)營業(yè)績不夠理想。公司對廣東耀皮日熔化量為550噸的浮法玻璃生產(chǎn)線進行停產(chǎn),并作冷修技術改造準備。6. 公司2008年度利潤分配方案為:A股每10股派0.20元人民幣(含稅);B股每股派0.002925美元(含稅)。股權登記日:2009年7月29日(A股);2009年8月3日(B股);除息日:2009年7月30日。十大股東播報編輯截至日期：2009-06-30 公告日期：2009-08-27編號股東名稱持股數(shù)量持股比例股本性質(zhì)1皮爾金頓國際控股公司BV14195.90萬19.41%流通A股2中國復合材料集團有限公司11893.46萬16.26%流通A股3上海耀華玻璃廠11799.71萬16.14%流通A股4上海建筑材料（集團）總公司7450.87萬10.19%流通A股5中國東方資產(chǎn)管理公司2836.84萬3.88%流通A股6TOYO SECURITIES ASIA LTD. A/C CLIENT909.40萬1.24%流通B股7孫文雄514.29萬0.70%流通B股8NAITO SECURITIES CO., LTD.494.02萬0.68%流通B股9申銀萬國證券股份有限公司421.33萬0.58%流通A股10李麗蓁250.79萬0.34%流通B股最大股東易主播報編輯證券代碼：600819 證券簡稱：耀皮玻璃 編號：臨2011-01900918 耀皮B 股上海耀華皮爾金頓玻璃股份有限公司關于國有股權無償劃轉(zhuǎn)過戶完成的公告本公司董事會及全體董事保證本公告內(nèi)容不存在任何虛假記載、誤導性陳述或者重大遺漏，并對其內(nèi)容的真實性、準確性和完整性承擔個別及連帶責任。本公司接到中國證券登記結算有限責任公司上海分公司過戶登記確認書，上海耀華玻璃廠所持本公司計117,997,072 股國有法人股無償劃轉(zhuǎn)給上海建材（集團）總公司的過戶手續(xù)已經(jīng)辦理完成。過戶完成后本公司總股本仍為731,250,082，其中上海建筑材料（集團）總公司持有192,505,795 股，占本公司總股本的26.33%，成為公司第一大股東。上述權益變動的具體情況詳見《上海耀華皮爾金頓玻璃股份有限公司詳式權益變動報告書》和《上海耀華皮爾金頓玻璃股份有限公司簡式權益變動報告書》。特此公告上海耀華皮爾金頓玻璃股份有限公司董事會2011 年1 月21 日新手上路成長任務編輯入門編輯規(guī)則本人編輯我有疑問內(nèi)容質(zhì)疑在線客服官方貼吧意見反饋投訴建議舉報不良信息未通過詞條申訴投訴侵權信息封禁查詢與解封?2024?Baidu?使用百度前必讀?|?百科協(xié)議?|?隱私政策?|?百度百科合作平臺?|?京ICP證030173號?京公網(wǎng)安備110000020000

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一站式藥物篩選平臺

虛擬篩選

基于細胞表型的活性篩選

離子通道篩選

激酶譜篩選

SPR 檢測服務

分子動力學模擬

GPCR 靶向藥物篩選

核受體藥物篩選

親和質(zhì)譜藥物篩選

DEL 合成與篩選

摩爾計算器

稀釋計算器

職業(yè)發(fā)展

Gene

SYP - synaptophysin Gene

SYP - synaptophysin Gene

基因

蛋白

疾病

相關產(chǎn)品

直系同源

中文名稱：突觸蛋白

種屬: Homo sapiens

同用名: MRX96; MRXSYP; XLID96

基因 ID: 6855

|

基因類型: protein coding

關于 SYP

Cytogenetic location: Xp11.23

Genomic coordinates (GRCh38): X:49,187,815-49,200,193 (from NCBI)

This gene has 11 transcripts (splice variants), 263 orthologues, 3 paralogues and is associated with 3 phenotypes. Biased expression in brain (RPKM 226.8) and adrenal (RPKM 21.1).

功能概要

該基因編碼大腦和內(nèi)分泌細胞中小突觸小泡的完整膜蛋白。該蛋白質(zhì)還結合膽固醇，并被認為可將囊泡相關膜蛋白 2 (synaptobrevin) 直接靶向細胞內(nèi)隔室。該基因的突變與 X 連鎖形式的認知障礙有關。[RefSeq 提供，2017 年 7 月]

This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds Cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]

SYP 基因產(chǎn)物(1)

mRNA

Protein

Name

NM_003179.3

NP_003170.1

synaptophysin

SYP 蛋白結構

MARVEL

MARVEL: Membrane-associating domain (22 - 221)

0

100

200

313?a.a.

蛋白主名

其他名稱

synaptophysin

major synaptic vesicle protein P38

關聯(lián)疾病

疾病名稱

別名

Intellectual Developmental Disorder, X-Linked 96

XLID96

Mental Retardation, X-Linked 96

Mrx96

Mental Retardation, X-Linked, Type 96

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability

Central Neurocytoma

Neurocytoma

Neurolipocytoma

Neurocytoma Central

Neuroendocrine Carcinoma

Neuroendocrine Cancer

Carcinoma Neuroendocrine

Carcinoma, Neuroendocrine

Olfactory Neuroblastoma

Esthesioneuroblastoma

Asthesioneuroblastoma

Esthesioneuroepithelioma

Olfactory Esthesioneuroblastoma

Paranasal Sinus Olfactory Neuroblastoma

Esthesioneuroblastoma, Olfactory

Esthesioneuroblastoma Of Nasal Cavity

Ganglioneuroma

Merkel Cell Carcinoma

Trabecular Adenocarcinoma

Cutaneous Neuroendocrine Carcinoma

Trabecular Carcinoma

Carcinoma, Merkel Cell

Merkel Cell Cancer

Merkle Tumors

Mcc

Carcinoma Merkel Cell

Adrenal Cortical Adenoma

Adrenocortical Adenoma

Adenoma Adrenocortical

Subependymal Giant Cell Astrocytoma

Sega

Astrocytoma Subependymal Giant Cell

Subependymal Giant-Cell Astrocytoma

Ganglioglioma

Childhood Ganglioglioma

Adult Ganglioglioma

Cns Ganglioglioma

Mixed Cell Tumors Containing Both Neural Ganglionic Cells And Neural Glial Cell Components

Large Cell Carcinoma

Carcinoma, Large Cell

Carcinoma Large Cell

Endocrine Gland Cancer

Endocrine Neoplasm

Malignant Neoplasm Of Endocrine Gland

Endocrine Gland Neoplasms

Endocrine Tumor

Malignant Endocrine Tumor

Malignant Tumour Of Endocrine Gland

Neoplasm Of Endocrine Gland

Neoplasm Of Endocrine System

Neoplasm Of The Endocrine System

Carcinoma Of Endocrine Gland

Binswanger'S Disease

Multi-Infarct Dementia

Dementia Multi-Infarct

Binswanger Disease

Sertoli Cell Tumor

Tubular Androblastoma

Neuroendocrine Tumor

Neuroendocrine Neoplasm

Neuroendocrine Tumors

Carcinoma, Neuroendocrine

Pulmonary Sclerosing Hemangioma

Pneumocytoma

Sclerosing Hemangioma

Sclerosing Haemangioma

Cutaneous Fibrous Histiocytoma

Paraganglioma

Chemodectoma

Glomus Body Tumor

Paragangliomas

Carotid Body Paraganglioma

Extra-Adrenal Paraganglioma

Pineoblastoma

Pineal Pnet

Pinealoma

Pineal Gland Neoplasm

Pineocytoma

Tumor Of The Pineal Region

Glomus Tumor

Glomus Neoplasm

Glomus Tumour

Large Cell Neuroendocrine Carcinoma

Rhabdoid Cancer

Rhabdoid Tumor

Malignant Rhabdoid Tumor

Malignant Rhabdoid Tumour

Rhabdoid Sarcoma

Rhabdoid Tumor Predisposition Syndrome 1

Rhabdoid Tumor Predisposition Syndrome 2

Atypical Teratoid Rhabdoid Tumor

Brain Tumor, Posterior Fossa, Of Infancy, Familial

Atypical Teratoid/Rhabdoid Tumor

Blastoma

Embryoma

Malignant Olfactory Nerve Neoplasm

Malignant Olfactory Nerve Tumor

Malignant Tumor Of Olfactory Nerve

Primary Malignant Neoplasm Of Olfactory Nerve

Nasal Cavity Cancer

Nasal Cavity Carcinoma

Malignant Neoplasm Of Nasal Cavities

Malignant Tumor Of The Nasal Cavity

Cancer Of Nasal Cavity

Carcinoma Of Nasal Cavity

Malignant Neoplasm Of Nasal Cavity

Neoplasm Of Nasal Cavity

Ganglioneuroblastoma

Hemangioblastoma

Capillary Hemangioblastoma

Pineocytoma

Pinealoma

Pinealocytoma

Pineal Gland Neoplasm

Tumor Of The Pineal Region

Middle Ear Adenoma

Adenoma Of Middle Ear

Adenoma Of The Middle Ear

Auditory System Benign Neoplasm

Neurofibroma

Neurofibromas

Neurofibromatoses

Nerve Sheath Tumors

Oligodendroglioma

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Oligodendroglial Tumors

Well Differentiated Oligodendroglioma

Breast Neuroendocrine Neoplasm

Neuroendocrine Tumor Of The Breast

Sensory Organ Benign Neoplasm

Pulmonary Large Cell Neuroendocrine Carcinoma

Large Cell Lung Neuroendocrine Carcinoma

Cerebral Neuroblastoma

Neuroblastoma Of Brain

Neuroblastoma Of Cerebrum

Neuroblastoma Of The Cerebral Hemisphere

Papillary Ependymoma

Ependymoma Papillary

Pulmonary Blastoma

Blastoma Of Lung

Pneumoblastoma

Lung Large Cell Carcinoma

Large Cell Carcinoma Of Lung

Large Cell Lung Carcinoma

Large Cell Lung Cancer

Esophageal Neuroendocrine Tumor

Esophageal Neuroendocrine Tumour

Neuroendocrine Tumor Of Esophagus

Neuroendocrine Tumour Of Oesophagus

Urinary Bladder Small Cell Neuroendocrine Carcinoma

Small Cell Neuroendocrine Carcinoma Of The Urinary Bladder

Small Cell/Neuroendocrine Carcinoma Of Urinary Bladder

Benign Teratoma

Dermoid Cyst

Cystic Dermoid Choristoma

Dermoid Choristoma

Mature Cystic Teratoma

Dermoid Tumour

Teratoma, Benign

Dermoid Cyst Of Ovary

Ampulla Of Vater Benign Neoplasm

Tumor Of The Ampulla Of Vater

Ureter Small Cell Carcinoma

Ureteral Small Cell Carcinoma

Papilloma Of Choroid Plexus

Choroid Plexus Papilloma

CPP

Childhood Choroid Plexus Papilloma

Papilloma Choroid Plexus

Papilloma, Choroid Plexus

Choroid Plexus Carcinoma

Duodenal Benign Neoplasm

Neoplasm Of Duodenum

Neoplasm Of The Duodenum

Cancer Of Duodenum

Ovarian Large-Cell Neuroendocrine Carcinoma

Non-Small-Cell Type Neuroendocrine Carcinoma Of Ovary

Ovarian Large Cell Neuroendocrine Carcinoma

Bladder Small Cell Carcinoma

Small Cell Bladder Cancer

Small Cell Carcinoma Of The Bladder

Poorly Differentiated Neuroendocrine Carcinoma Of The Bladder

Sccb

Small Cell Bladder Carcinoma

Small Cell Carcinoma Of The Urinary Bladder

Tuberous Sclerosis

Tuberous Sclerosis Syndrome

Bourneville'S Disease

Epiloia

Cerebral Sclerosis

Tuberose Sclerosis

Tuberous Sclerosis 1

Bourneville Disease

Bourneville Phakomatosis

Pringle'S Disease

Cranial Nerve Malignant Neoplasm

Cranial Nerve Neoplasms

Malignant Neoplasm Of Cranial Nerve

Malignant Tumor Of Cranial Nerve

Malignant Tumor Of The Cranial Nerve

Cellular Ependymoma

Ependymoma

Classic Ependymoma

Papillary Ependymoma

Tanycytic Ependymoma

Clear Cell Ependymoma

Ependymoma, Familial

Epithelial Ependymoma

Who Grade Ii Ependymal Neoplasm

Ovarian Mucinous Adenofibroma

Ovarian Mucinous Cystadenofibroma

Sertoli-Leydig Cell Tumor

Sertoli-Leydig Cell Tumors

Androblastoma Of Ovary

Arrhenoblastoma

Arrhenoblastoma Of Ovary

Sertoli-Leydig Cell Tumor Of The Ovary

Sertoli-Leydig Cell Tumor Of Intermediate Differentiation

Sertoli-Leydig Cell Tumor Of Ovary

Sweat Gland Cancer

Sweat Gland Carcinoma

Malignant Neoplasm Of Sweat Gland

Malignant Tumor Of The Sweat Gland

Carcinoma Of The Sweat Gland

Primary Malignant Neoplasm Of Sweat Gland

Sweat Gland Neoplasms

Pheochromocytoma

Pheochromocytoma, Susceptibility To

Phaeochromocytoma

Adrenal Gland Chromaffin Paraganglioma

Adrenal Gland Chromaffinoma

Adrenal Gland Paraganglioma

Adrenal Gland Pheochromocytoma

Chromaffin Paraganglioma Of The Adrenal Gland

Intraadrenal Paraganglioma

PCC

Chromaffin Cell Tumor

Medullary Chromaffinoma

Medullary Paraganglioma

Pheochromoblastoma

Pheochromocytomas

Chromaffin Cell Neoplasm

Pheochromocytoma, Malignant

Pineal Gland Cancer

Tumor Of The Pineal Region

Malignant Pineal Region Tumor

Malignant Tumor Of Pineal Gland

Neoplasm Of Pineal Gland

Neoplasm Of The Pineal Region

Pineal Body Neoplasm

Pineocytic Tumor

Malignant Neoplasm Of Pineal Gland

Pineal Gland Neoplasm

Pineocytoma

Basaloid Squamous Cell Carcinoma

Basaloid Carcinoma

Melanotic Neuroectodermal Tumor

Melanotic Neuroectodermal Tumor Of Infancy

Neuroectodermal Tumor, Melanotic

Infantile Melanotic Neuroectodermal Neoplasm

Melanotic Neuroectodermal Tumour

Melanotic Neuroectodermal Tumour Of Infancy

Pigmented Neuroectodermal Tumour Of Infancy

Pulmonary Neuroendocrine Tumor

Neuroendocrine Neoplasm Of Lung

Thymic Carcinoma

Malignant Thymoma

Thymoma, Malignant

Supratentorial Cancer

Supratentorial Neoplasms

Brain Neoplasm, Supratentorial

Malignant Supratentorial Tumor

Cancer, Supratentorial

Cerebrum Cancer

Cerebral Cancer

Neoplasm Of Cerebrum

Tumor Of Cerebrum

Malignant Neoplasm Of Cerebrum

Cerebellar Liponeurocytoma

Lipomatous Medulloblastoma

Central Neurocytoma

Islet Cell Tumor

Pancreatic Neuroendocrine Tumor

Neuroendocrine Tumor Of Pancreas

Pnet

Pancreatic Net

Pancreatic Endocrine Tumor

Well-Differentiated Nen Of Pancreas

Well-Differentiated Neuroendocrine Neoplasm Of Pancreas

Well-Differentiated Pancreatic Nen

Well-Differentiated Pancreatic Neuroendocrine Neoplasm

Endocrine Pancreas Cancer

Islet Cell Neoplasm

Islet Cell Tumour

Malignant Pancreatic Endocrine Tumor

Malignant Pancreatic Endocrine Tumour

Malignant Tumor Of Endocrine Pancreas

Malignant Tumour Of Endocrine Pancreas

Pancreatic Endocrine Neoplasm

Pancreatic Neuroendocrine Neoplasm

Adenoma, Islet Cell

Well Differentiated Pancreatic Endocrine Tumor

Malignant Neoplasm Of Endocrine Pancreas

Pancreatic Endocrine Carcinoma

Medullomyoblastoma

Breast Papillary Carcinoma

Breast Solid Papillary Carcinoma

Papillary Carcinoma Of Breast

Papillary Carcinoma Of The Breast

Solid Papillary Carcinoma Of The Breast

Pineal Parenchymal Tumor Of Intermediate Differentiation

Pineal Parenchymal Tumour Of Intermediate Differentiation

Pineal Parenchymal Tumors Of Intermediate Differentiation

Pptid

Auditory System Cancer

Ear Neoplasms

Carcinoid Tumors, Intestinal

Carcinoid

Gastrointestinal Carcinoid Tumor

Argentaffinoma

Intestinal Carcinoid Tumor

ICT

Tumor, Carcinoid, Intestinal

Malignant Carcinoid Syndrome

Carcinoid Tumor Of Intestine

Carcinoid Tumor

Carcinoid Tumor No Icd-O Subtype

Small Cell Cancer Of The Lung

Small Cell Lung Cancer

Small Cell Lung Carcinoma

Sclc

Small-Cell Cancer Of Lung

Lung Small Cell Carcinoma

Sclc1

Sccl

Cancer, Lung, Small Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Mixed Ductal-Endocrine Carcinoma

Carotid Body Cancer

Cancer Of Carotid Body

Malignant Carotid Body Paraganglioma

Malignant Carotid Body Tumor

Malignant Neoplasm Of Carotid Body

Gangliocytoma

Ganglioneuroma

Gangliocytoma Of Central Nervous System

Gastrointestinal Neuroendocrine Tumor

Gastrointestinal Neuroendocrine Tumour

Malignant Gastrointestinal Neuroendocrine Tumor

Malignant Gastrointestinal Neuroendocrine Tumour

Digestive System Neuroendocrine Neoplasm

Digestive System Neuroendocrine Tumor

Obstructive Hydrocephalus

Endometrial Small Cell Carcinoma

Sinonasal Undifferentiated Carcinoma

Highly Aggressive Undifferentiated Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Snuc

Pancreatoblastoma

Cauda Equina Neoplasm

Tumor Of The Cauda Equina

Neoplasm Of Cauda Equina

Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain

Paranasal Sinus Cancer

Paranasal Sinus Adenoid Cystic Carcinoma

Paranasal Sinus Mucoepidermoid Carcinoma

Paranasal Sinus Squamous Cell Carcinoma

Paranasal Sinus Neoplasms

Adenoid Cystic Carcinoma Of Accessory Sinus

Adenoid Cystic Carcinoma Of Paranasal Sinus

Epidermoid Carcinoma Of The Paranasal Sinus

Mucoepidermoid Carcinoma Of Accessory Sinus

Paranasal Sinus Adenocarcinoma

Squamous Cell Carcinoma Of Paranasal Sinus

Paranasal Sinus Neoplasm

Adenocarcinoma Of Accessory Sinus

Gallbladder Small Cell Carcinoma

Oat Cell Carcinoma Of The Gallbladder

Gallbladder Small Cell Neuroendocrine Carcinoma

Colon Neuroendocrine Neoplasm

Colonic Neuroendocrine Tumor

Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob Disease

CJD

Bovine Spongiform Encephalopathy

Vcjd

Inherited Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Familial

Creutzfeldt Jakob Disease

Creutzfeldt-Jacob Disease

Creutzfeldt Jacob Disease

Sporadic Creutzfeldt-Jakob Disease

Encephalopathy, Bovine Spongiform

Creutzfeldt-Jakob Disease, Variant, Resistance To

Creutzfeldt-Jakob Disease, Variant

Creutzfeldt Jacob Syndrome

Jakob-Creutzfeldt Disease

Subacute Spongiform Encephalopathy

Transmissible Virus Dementia

New Variant Of Cjd

Nv-Cjd

Variant Cjd

Variant Creutzfeldt-Jacob Disease

Sporadic Cjd

Inherited Cjd

Acquired Creutzfeldt-Jakob Disease

Variant Mcj

Encephalopathy Bovine Spongiform

Familial Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Syndrome

New Variant Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Sporadic

Acquired Cjd

Scjd - [Sporadic Creutzfeldt-Jakob Disease]

Idiopathic Creutzfeldt-Jakob Disease

Creutzfeld-Jakob Disease Nos

Vcjd - [Variant Creutzfeldt-Jakob Disease]

Cystadenoma

Cystoma

Craniopharyngioma

Gastric Small Cell Carcinoma

Small Cell Carcinoma Of Stomach

Spinal Muscular Atrophy, Type I

Werdnig-Hoffmann Disease

SMA1

Spinal Muscular Atrophy 1

Sma I

Sma, Infantile Acute Form

Muscular Atrophy, Infantile

Spinal Muscular Atrophy-1

Hmn Proximal Type I

Infantile Muscular Atrophy

Proximal Spinal Muscular Atrophy Type 1

Sma Type 1

Sma Type I

Sma-I

Hereditary Motor Neuropathy Proximal Type I

Progressive Muscular Atrophy Of Infancy

Proximal Spinal Muscular Atrophy, Type 1

Werdnig Hoffmann Disease

Infantile Spinal Muscular Atrophy

Infantile-Onset Spinal Muscular Atrophy

Proximal Hereditary Motor Neuropathy Type I

Sma Infantile Acute Form

Spinal Muscular Atrophy Type I

Werdnig-Hoffman Disease

Atrophy, Muscular, Spinal, Type 1

Acinar Cell Cystadenocarcinoma

Pancreatic Acinar Cell Cystadenocarcinoma

Leydig Cell Tumor

Leydig Cell Neoplasm

Tumor, Leydig Cell

Leydig Cell Tumor, Benign

Adrenal Carcinoma

Adrenal Cancer

Adrenal Gland Cancer

Malignant Neoplasm Of Adrenal Gland

Adrenal Gland Neoplasms

Carcinoma Of The Adrenal Gland

Adrenal Neoplasm

Malignant Adrenal Tumor

Neoplasm Of Adrenal Gland

Tumor Of The Adrenal Gland

Adrenal Gland Neoplasm

Adrenocortical Carcinoma

Adrenal Gland Malignancy

Suprarenal Cancer

Malignant Neoplasm Of Suprarenal Gland

Malignant Neoplasm Of Adrenal Gland, Unspecified

Malignant Tumour Of Adrenal Gland

Suprarenal Gland Cancer

Primary Malignant Neoplasm Of Adrenal Gland

Lung Benign Neoplasm

Lung Neoplasms

Tumor Of The Lung

Lung Tumor

Cervix Small Cell Carcinoma

Small Cell Carcinoma Of The Cervix

Small Cell Carcinoma Of The Cervix Uteri

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Pancreatic Acinar Cell Adenocarcinoma

Pancreatic Acinar Cell Carcinoma

Acinar Cell Adenocarcinoma Of The Pancreas

Appendix Carcinoid Tumor

Appendix Carcinoid Endocrine Tumour

Carcinoid Tumor Of Appendix

Medulloepithelioma

Diktyoma, Malignant

Medulloepithelioma, Central Nervous System

Medulloepithelioma Of The Central Nervous System

Granular Cell Tumor

Abrikosov'S Tumor

Neoplasm Of Granular Cell

Abrikosoff'S Granulous Cell Tumor

Abrikosoff'S Tumor

Giant Granulocellular Abrikosov'S Tumor

Malignant Variant Of Abrikosov'S Tumor

Carcinoma, Granular Cell

Mediastinal Cancer

Mediastinal Neoplasms

Mediastinal Tumor

Mediastinum Cancer

Neoplasm Of Mediastinum

Tumour Of Mediastinum

Malignant Tumor Of Mediastinum

Glomangiosarcoma

Malignant Glomus Neoplasm

Glomus Tumor, Malignant

Pilocytic Astrocytoma

Juvenile Pilocytic Astrocytoma

Grade I Astrocytic Tumor

Piloid Astrocytoma

Peripheral Nervous System Benign Neoplasm

Autonomic Nervous System Benign Neoplasm

Teratoma

Teratomas

Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration

Tubular Adenocarcinoma

Tubular Carcinoma

Adenocarcinoma Tubular

Adenocarcinoma, Tubular

Adrenal Neuroblastoma

Neuroblastoma Of Adrenal Gland

Adrenal Gland Neuroblastoma

Neuroblastoma Nos

Cerebrovascular Benign Neoplasm

Benign Perivascular Tumor

Benign Pericytic Neoplasm

Ovarian Germ Cell Teratoma

Germ Cell Teratoma Of Ovary

Ovarian Teratoma

Central Nervous System Primitive Neuroectodermal Neoplasm

Cpnet

Glomangioma

Malignant Melanocytic Neoplasm Of The Peripheral Nerve Sheath

Melanotic Malignant Nerve Sheath Tumor

Melanocytic Mpnst

Melanotic Malignant Peripheral Nerve Sheath Tumor

Melanotic Malignant Peripheral Nerve Sheath Tumour

Adenoma

Acinar Cell Adenoma

Adenomas

Acinic Cell Adenoma

Glomangiomyoma

Gastrointestinal Neuroendocrine Benign Tumor

Gastrinoma

Gastrin Cell Tumour

Gastrin Secreting Tumor

Malignant Gastrinoma

Gastrinoma, Malignant

Multiple Endocrine Neoplasia

Men

Multiple Endocrine Adenomatosis

Multiple Endocrine Neoplasia Syndrome

Adenomatosis, Familial Endocrine

Endocrine Neoplasia, Multiple

Familial Endocrine Adenomatosis

Mea

Multiple Endocrine Neoplasms

Multiple Endocrine Neoplasia Type 1

Spinal Cord Oligodendroglioma

Oligodendroglioma Of Spinal Cord

Well Differentiated Spinal Cord Oligodendroglioma

Extraosseous Ewing Sarcoma

Extraosseous Ewing'S Sarcoma

Extraosseous Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Extraskeletal Ewing Sarcom

Sarcoma Extraosseous Ewings

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Conn'S Syndrome

Cushing Syndrome

Hyperaldosteronism

Primary Hyperaldosteronism

Hypercortisolism

Primary Aldosteronism

Cushing'S Syndrome

Adrenal Gland Hyperfunction

Conn Syndrome

Hyperadrenalism

Ectopic Acth Syndrome

Hyperadrenocorticism

Cushing Disease

Cushing'S Disease

Adrenal Cortex Adenoma

Corticotroph Pituitary Adenoma

Pituitary Corticotroph Micro-Adenoma

Pituitary-Dependent Cushing Syndrome

Pituitary Acth Hypersecretion

Acth Syndrome, Ectopic

Acth-Secreting Pituitary Adenoma

Adrenal Hyperfunction Resulting From Pituitary Acth Excess

Ectopic Adrenocorticotropic Hormone Syndrome

Nodular Primary Adrenocortical Dysplasia

Pituitary Dependent Cushing Syndrome

Pituitary Cushing Syndrome

Pituitary-Dependant Cushing Syndrome

Pituitary-Dependant Hypercortisolism

Pituitary-Dependant Hypercortisolism Disorder

Aldosteronism Primary

Acth Syndrome Ectopic

Adrenal Cushing'S Syndrome

Adrenal Cortical Adenoma

Cushing Syndrome Nos

Cortisol Hypersecretion

Corticoadrenal Hypersecretion

Cushing Syndrome Secondary To Ectopic Acth-Secretion

Ectopic Cushing Syndrome

Hypercortisolism Due To Nonpituitary Tumour

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion Causing Cushing Syndrome

Idiopathic Aldosteronism

Aldosteronism

Primary Aldosteronism Due To Bilateral Adrenal Hyperplasia

Primary Aldosteronism Due To Adrenal Hyperplasia

Ovary Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Ovary

Laryngeal Small Cell Carcinoma

Small Cell Carcinoma Of Larynx

Choroid Plexus Cancer

Choroid Plexus Carcinoma

Choroid Plexus Neoplasms

Choroid Plexus Neoplasm

Tumor Of Choroid Plexus

Tumor Of The Choroid Plexus

Choroid Plexus Tumor

Choroid Plexus Tumors

Anaplastic Choroid Plexus Papilloma

Choroid Plexus Papilloma Nos

Papilloma Of Choroid Plexus

Plexus Choroideus Papilloma

Choroid Plexus Papilloma In Fourth Ventricle

Plexus Choroideus Papilloma In Fourth Ventricle

Dysembryoplastic Neuroepithelial Tumor

Dysembryoplastic Neuroepithelial Tumour

Dysembryoplastic Neuroepithelial Neoplasm

Dnet

Chordoid Meningioma

Meningioma, Chordoid

Carcinosarcoma

Mixed Tumor, Mullerian

Malignant Mixed Mesodermal Tumor

Malignant Mixed Mullerian Tumor

Mmmt

Mixed Tumor, Mesodermal

Mesodermal Mixed Tumor

Mixed Mesodermal Tumor

Mullerian Mixed Tumor

Mixed Mullerian Tumor

Malignant Mixed Müllerian Tumor

Mixed Müllerian Tumor

Mixed Tumor Mullerian

Mixed Tumor, Not Otherwise Specified

Vagus Nerve Neoplasm

Neoplasm Of Vagus Nerve

Vagus Nerve Tumors

Anal Neuroendocrine Tumor

Anal Neuroendocrine Tumour

Neuroendocrine Tumor Of Anus

Neuroendocrine Tumour Of Anus

Anal Canal Neuroendocrine Tumor

Hemangioma

Hemangiomas

Adrenal Cortical Carcinoma

Adrenocortical Carcinoma

Adrenal Cortex Carcinoma

Carcinoma Of The Adrenal Cortex

Acc

Adrenocortical Cancer

Carcinoma Adrenocortical

Thymus Small Cell Carcinoma

Small Cell Carcinoma Of The Thymus

Thymic Small Cell Carcinoma

Small Cell Carcinoma

Small Cell Carcinoma, Intermediate Cell

Intermediate Cell Small Cell Carcinoma

Small Cell Carcinoma - Intermediate Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Prostate Neuroendocrine Neoplasm

Neuroendocrine Tumor Of The Prostate

Intestinal Pseudo-Obstruction

Chronic Intestinal Pseudoobstruction

Chronic Intestinal Pseudo-Obstruction

Cipo

Neuronal Intestinal Dysplasia

Hollow Visceral Myopathy

Familial Visceral Neuropathy

Paralytic Ileus

Intestinal Pseudoobstruction

Chronic Idiopathic Intestinal Pseudo-Obstruction

Ciip

Congenital Short Bowel Syndrome

Enteric Neuropathy

Familial Visceral Myopathy

Ipo

Pseudo-Obstruction Of Intestine

Pseudointestinal Obstruction Syndrome

Pseudoobstructive Syndrome

Congenital Idiopathic Intestinal Pseudoobstruction

Visceral Myopathy, Familial

Cystic Teratoma

Dermoid Cyst

Benign Teratoma

Neuronal Intestinal Dysplasia, Type B

Neuronal Intestinal Dysplasia Type B

Nid B

Gastrointestinal Stromal Tumor

GIST

Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Sarcoma

Gastrointestinal Stromal Tumor, Familial

Gant

Gastrointestinal Stromal Tumour

Stromal Tumor Of Gastrointestinal Tract

Stromal Tumour Of Gastrointestinal Tract

Gastrointestinal Stromal Neoplasm

Paraganglioma And Gastric Stromal Sarcoma

Plexosarcoma

Cerebellum Cancer

Cerebellar Neoplasms

Cerebellar Cancer

Malignant Tumor Of Cerebellum

Malignant Neoplasm Of Cerebellum

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Supratentorial Primitive Neuroectodermal Tumor

Supratentorial Pnet

Supratentorial Embryonal Tumor, Not Otherwise Specified

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Glomangiomatosis

Askin'S Tumor

Askin Tumor

Askin Tumour

Askin'S Tumour

Clear Cell Ependymoma

Cellular Ependymoma

Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Microcystic Adenoma

Adenoma Microcystic

Adenoma, Microcystic

Adrenogenital Syndrome

Adrenogenital Disease

Adrenogenital Syndrome Nos

Gastric Neuroendocrine Neoplasm

Gastric Neuroendocrine Tumor

Neuroendocrine Tumor Of The Stomach

Neuroendocrine Tumor Of Stomach

Gnet

Gastric Net

Net Of Stomach

Mucinous Adenofibroma

Cervical Large Cell Neuroendocrine Carcinoma

Cloacogenic Carcinoma

Cloacogenic Anal Carcinoma

Myocardium Cancer

Malignant Myocardial Tumor

Malignant Neoplasm Of Myocardium

Tumor Of Myocardium

Malignant Tumor Of Myocardium

Embryonal Tumor With Multilayered Rosettes, C19mc-Altered

Ependymoblastoma

Hirschsprung Disease 1

Hirschsprung Disease

Aganglionic Megacolon

Hscr

Hirschsprung'S Disease

Congenital Megacolon

Congenital Intestinal Aganglionosis

Colonic Aganglionosis

Hirschsprung Disease, Susceptibility To, 1

Hirschsprung Disease, Protection Against

HSCR1

Mgc

Pelvirectal Achalasia

Total Intestinal Aganglionosis

Megacolon, Aganglionic

Macrocolon

Hscr 1

Hirschsprung Disease Type 1

Hirschsprung Disease, Type 1

Congenital Dilatation Of Colon

Aganglionosis

Congenital Aganglionic Megacolon

Aganglionosis Of Colon

Bowel Aganglionosis

Colon Aganglionosis

Hirschsprung Megacolon

Laryngeal Neuroendocrine Tumor

Laryngeal Neuroendocrine Tumour

Neuroendocrine Tumor Of Larynx

Neuroendocrine Tumour Of Larynx

Neuroendocrine Neoplasm Of Larynx

Papillary Squamous Carcinoma

Papillary Epidermoid Carcinoma

Papillary Squamous Cell Carcinoma

Chiari Malformation

Dementia

Dementias

Presenile Dementia

Alzheimer Type Dementia

Alzheimer Sclerosis

Alzheimer Disease Dementia

Alzheimer Dementia

Primary Degenerative Alzheimer Type Dementia

End Stage Alzheimer'S Dementia

Alzheimer'S Type Atypical Dementia

Alzheimer Type Presenile Dementia

Early Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 2

Dementia In Alzheimer Disease With Early Onset

Early Onset Alzheimer Type Dementia, Uncomplicated

Primary Degenerative Alzheimer Type Dementia, Early Onset

Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

Alzheimer Disease Dementia With Early Onset

Presenile Sclerosis

Presenile Brain Sclerosis

Presenile Alzheimer Brain Sclerosis

Late Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 1

Dementia In Alzheimer Disease With Late Onset

Primary Degenerative Alzheimer Type Dementia, Late Onset

Sdat - [Senile Dementia, Alzheimer Type]

Alzheimer Disease Dementia With Late Onset

Late Onset Alzheimer Brain Sclerosis

Senile Alzheimer Brain Disease

Senile Alzheimer Brain Sclerosis

Senile Primary Degenerative Alzheimer Type Dementia

Senile Dementia Of The Alzheimer Type

Arteriosclerotic Dementia

Strategic-Infarct Dementia

Post Stroke Dementia

Vascular Cognitive Impairment

Vascular Dementia

Dementia Of The Lewy Body Type

Dementia With Lewy Bodies

Sdlt - [Senile Dementia Of The Lewy Body Type]

Senile Dementia Of The Lewy Body Type

Alcohol-Related Dementia

Alcoholic Dementia Nos

Alcohol-Induced Dementia

Alcoholic Brain Syndrome

Chronic Alcoholic Brain Syndrome

Alcohol Dementia

Late Onset Alcoholic Psychosis

Residual And Late-Onset Alcohol-Induced Psychotic Disorder

Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

Late-Onset Psychoactive Substance-Induced Psychotic Disorder

Inhalant Dementia

Volatile Solvents Dementia

Dementia In Paralysis Agitans

Pdd - [Parkinson Disease Dementia]

Dementia Syndrome Of Parkinson Disease

Dementia In Parkinson Disease

Parkinson Related Dementia

Dementia In Huntington Chorea

Hiv - [Human Immunodeficiency Virus] Dementia

Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

Aids Related Dementia

Dementia Due To Niacin Deficiency

Extra-Adrenal Pheochromocytoma

Pheochromocytoma, Extra-Adrenal

Perivascular Tumor

Malignant Perivascular Cancer

Carcinoid Syndrome

Carcinoid Tumor

Malignant Carcinoid Syndrome

Carcinoid Tumor Syndrome

Carcinoid Tumors

Carcinoid Tumor No Icd-O Subtype

Argentaffinoma Syndrome

Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive

Hydrocephalus, X-Linked

Hydrocephalus Adverse Event

Hydrocephaly Nos

Malignant Teratoma

Immature Teratoma

Malignant Extragonadal Teratoma

Primary Malignant Extragonadal Teratoma

Teratoma, Malignant, Nos

Teratoma, Malignant

Immature Extragonadal Teratoma

Lung Meningioma

Lung Primary Meningioma

Primary Pulmonary Meningioma

Pulmonary Meningioma

Primary Lung Meningioma

Oncocytoma

Oxyphilic Adenoma

Follicular Adenoma, Oxyphilic Cell

Adenoma, Oxyphilic

Hurthle Cell Tumor

Oncocytic Neoplasm

Extraosseous Chondrosarcoma

Extraskeletal Myxoid Chondrosarcoma

Partial Cryptophthalmia

Incomplete Cryptophthalmos

Jejunal Neoplasm

Jejunal Tumor

Neoplasm Of Jejunum

Tumor Of Jejunum

Rhabdoid Meningioma

Papillary Meningioma

Meningioma, Rhabdoid

Small Intestine Benign Neoplasm

Neoplasm Of Small Intestine

Small Intestinal Neoplasm

Neoplasm Of The Small Intestine

Small Bowel Cancer

Small Intestine Cancer

Malignant Neoplasm Of Small Intestine, Unspecified

Malignant Tumour Of Small Bowel

Malignant Tumour Of Small Intestine

Primary Malignant Neoplasm Of Meckel Diverticulum

Benign Ependymoma

Ependymoma

Epithelial Ependymoma

Who Grade Ii Ependymal Tumor

Myxopapillary Ependymoma

Ectomesenchymoma

Rhabdomyosarcoma With Ganglionic Differentiation

Malignant Ectomesenchymoma

Thymoma

Primary Thymic Epithelial Neoplasm

Primary Thymic Epithelial Tumor

Thymus Neoplasms

Krukenberg Carcinoma

Krukenberg Tumor

Krukenberg Neoplasm

Krukenberg'S Tumor

Central Nervous System Mesenchymal Non-Meningothelial Tumor

Central Nervous System Mesenchymal Non-Meningothelial Tumour

Non-Meningothelial Mesenchymal Tumor

Non-Meningothelial Mesenchymal Tumour

Nodular Ganglioneuroblastoma

Ganglioneuroblastoma, Nodular

Motor Neuron Disease

Anterior Horn Cell Disease

Motor Neuron Diseases

Mnd - [Motor Neurone Disease]

Lou Gehrig Disease

Creeping Palsy

Creeping Paralysis

Bulbar Motor Neuron Disease

Bulbar Syndrome

Anterior Horn Cell Disorder

Hereditary Motor Neuron Disease

Malignant Pheochromocytoma

Pheochromocytoma, Malignant

Atypical Teratoid Rhabdoid Tumor

Rhabdoid Tumor Predisposition Syndrome

Rtps

Atypical Teratoid/Rhabdoid Tumor

Rhabdoid Predisposition Syndrome

Familial Posterior Fossa Brain Tumor Of Infancy

Familial Rhabdoid Tumor

At/Rt

Atypical Teratoid Rhabdoid Tumour

Atypical Teratoid/Rhabdoid Tumour

Rhabdoid Tumor Of The Cns

Rhabdoid Tumour Of The Cns

Familial Posterior Fossa Brain Tumor Syndrome

Hereditary Swi/Snf Deficiency Syndrome

Atrt

Adrenal Medulla Cancer

Adrenal Medulla Neoplasm

Adrenal Medulla Tumor

Malignant Neoplasm Of Adrenal Medulla

Malignant Tumor Of The Adrenal Medulla

Adrenal Medulla Carcinoma

Neoplasm Of Adrenal Medulla

Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site

Lung Oat Cell Carcinoma

Oat Cell Carcinoma

Carcinoma Oat Cell

Carcinoma, Small Cell

Mixed Cell Type Cancer

Malignant Mixed Neoplasm

Malignant Mixed Tumor

Mixed Neoplasm

Mixed Tumor, Malignant

Malignant Mixed Cancer

Mixed Tumor

Malignant Mixed Tumor, Not Otherwise Specified

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Clear Cell Meningioma

Anal Paget'S Disease

Anal Paget Disease

Paget'S Disease Of Anus

Paget'S Disease Of The Anus

Paget Disease Of The Anus

Breast Ductal Carcinoma

Ductal Breast Carcinoma

Duct Carcinoma

Carcinoma, Ductal

Mammary Ductal Carcinoma

Ductal Carcinoma

Inner Ear Disease

Labyrinthine Dysfunction

Diseases Of Inner Ear

Labyrinthine Disease

Abnormality Of The Inner Ear

Labyrinth Diseases

Labyrinthine Disorder

Nonfunctioning Labyrinth

Labyrinthine Loss Of Function

Labyrinthine Syndrome

Labyrinthine Disorder Nos

Intracranial Primitive Neuroectodermal Tumor

Intracranial Pnet

Intracranial Primitive Neuroectodermal Neoplasm

Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms

Insulinoma

Islet Cell Adenoma

Insulin-Producing Tumor Of Islet Cells

Adenoma Islet Cell

Islet Cell Tumor

Experimental Organism Islet Cell Adenoma Neoplasm

Chondrosarcoma, Extraskeletal Myxoid

Extraskeletal Myxoid Chondrosarcoma

Emc

Myxoid Extraosseous Chondrosarcoma

Ovarian Germ Cell Cancer

Ovarian Germ Cell Tumor

Malignant Germ Cell Tumor Of Ovary

Germ Cell Neoplasm Of Ovary

Germ Cell Tumor Of Ovary

Mogct

Malignant Ovarian Germ Cell Tumor

Malignant Ovarian Germ Cell Neoplasm

Lymphoepithelioma-Like Carcinoma

Lymphoepithelial Carcinoma

Nasopharyngeal Type Undifferentiated Carcinoma

Keratinizing Squamous Cell Carcinoma

Squamous Cell Carcinoma, Keratinizing

Keratinizing Epidermoid Carcinoma

Pancreatic Gastrinoma

Pancreatic G-Cell Tumor

Appendix Adenocarcinoma

Cystadenocarcinoma

Mucinous Adenocarcinoma

Adenocarcinoma Of Appendix

Appendiceal Adenocarcinoma

Adenocarcinoma Of The Appendix

Colonic Type Adenocarcinoma

Nonmucinous Adenocarcinoma

Mature Teratoma Of The Ovary

Ovarian Small Cell Carcinoma

Small Cell Carcinoma Of The Ovary

Scco

Small Cell Ovarian Carcinoma

Cerebellar Hypoplasia

Pancreatic Endocrine Carcinoma

Carcinoma Of Endocrine Pancreas

Islet Cell Carcinoma

Malignant Neoplasm Of Islets Of Langerhans

Pancreatic Neuroendocrine Carcinoma

Carcinoma Islet Cell

Carcinoma, Islet Cell

Mature Teratoma

Dermoid Cyst

Benign Teratoma

Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Vulvar Eccrine Porocarcinoma

Desmoplastic Small Round Cell Tumor

Dsrct

Desmoplastic Small Round-Cell Tumor

Desmoplastic Small Round-Cell Neoplasm

Thymus Basaloid Carcinoma

Basaloid Carcinoma Of The Thymus

Thymic Basaloid Carcinoma

Cecal Disease

Cecal Diseases

Disorder Of Cecum

Desmoplastic Nodular Medulloblastoma

Medulloblastoma With Extensive Nodularity

Nodular Medulloblastoma

Desmoplastic/Nodular Medulloblastoma

Mben

Medulloblastoma, With Extensive Nodularity

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia

Acinar Cell Carcinoma

Acinic Cell Carcinoma

Acinic Cell Tumor

Carcinoma Acinar Cell

Carcinoma, Acinar Cell

Acinar Cell Tumor

Esophageal Atresia

Tracheoesophageal Fistula

Congenital Atresia Of Esophagus

Congenital Imperforate Esophagus

Imperforate Esophagus

Oesophageal Atresia

Te Fistula

Tef

Tracheoesophageal Fistula With Or Without Esophageal Atresia

Ectopic Cushing Syndrome

Cushing Syndrome Due To Ectopic Acth Secretion

Ectopic Acth Secreting Tumor

Adrenocorticotropic Hormone Secretion Syndrome

Occult Ectopic Acth Secretion

Paraneoplastic Cushing Syndrome

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

Cranial Nerve Palsy

Cranial Nerve Paralysis

Cranial Nerve Diseases

Cranial Nerve Palsies

Prostatic Acinar Adenocarcinoma

Acinar Prostate Adenocarcinoma

Chordoid Glioma

Chordoid Glioma Of The Third Ventricle

Central Nervous System Benign Neoplasm

Benign Neoplasm Of The Central Nervous System

Prostate Small Cell Carcinoma

Small Cell Carcinoma Of Prostate

Prostate Oat Cell Carcinoma

Struma Ovarii

Duodenal Gastrinoma

Duodenal G-Cell Gastrin Producing Tumor

Gastrinoma Of Duodenum

Malignant Duodenal Gastrinoma

Duodenal Gastrin-Producing Neuroendocrine Tumor

Meibomian Cyst

Chalazion

Meibomian Gland Lipogranuloma

Tarsal Cyst

Rectum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Rectum

Rectal Squamous Cell Carcinoma

Squamous Carcinoma Of Rectum

Endocrine Organ Benign Neoplasm

Prostate Stromal Sarcoma

Stromal Sarcoma Of The Prostate

Subleukemic Leukemia

Aleukemic Leukemia Cutis

Leukemia Subleukemic

Adenosquamous Prostate Carcinoma

Adenosquamous Carcinoma Of Prostate

Adenosquamous Carcinoma Of The Prostate

Rhabdomyosarcoma

Lung Combined Large Cell Neuroendocrine Carcinoma

Combined Large Cell Neuroendocrine Carcinoma Of Lung

Pulmonary Combined Large Cell Neuroendocrine Carcinoma

Combined Large Cell Lung Neuroendocrine Carcinoma

Lumbosacral Plexus Lesion

Lumbosacral Plexus Lesions

Pleomorphic Xanthoastrocytoma

Pxa

Pleomorphic Xantho-Astrocytoma

Cauda Equina Syndrome

Cauda Equina

Polyradiculopathy

Skin Carcinoma

Skin Cancer

Carcinoma Of Skin

Ca - Skin Cancer

Cancer Of Skin

Malignant Neoplasm Of Skin

Melanoma And Non-Melanoma Skin Cancer

Skin Cancers

Cancer, Skin

Mucinous Cystadenofibroma

Endometrial Transitional Cell Carcinoma

Pancreas Lymphoma

Lymphoma Of Pancreas

Bilateral Hypoactive Labyrinth

Hypoactive Bilateral Labyrinthine Dysfunction

Hypoactive Labyrinth, Bilateral

Tracheal Cancer

Tracheal Carcinoma

Malignant Neoplasm Of Trachea

Tracheal Neoplasms

Pancoast Tumor

Pulmonary Sulcus Neoplasm

Pancoast Syndrome

Small Cell Osteogenic Sarcoma

Small Cell Osteosarcoma

Round Cell Osteosarcoma

Osteosarcoma Small Cell

Cystitis Cystica

Extracranial Neuroblastoma

Neural Tube Defects

Spina Bifida

Neural Tube Defect

NTD

Neural Tube Defects, Susceptibility To

Spinal Dysraphism

Spina Bifida, Susceptibility To

Rachischisis

Cleft Spine

Open Spine

Hydrocele Spinalis

Neural Tube Defect Nos

Sb - [Spina Bifida]

Spinal Hernia Nos

Spinal Fissure Nos

Orbital Cancer

Malignant Neoplasm Of Orbit

Orbital Tumor

Orbital Neoplasms

Neoplasm Of Orbit Proper

Orbit Cancer

Primary Malignant Neoplasm Of Orbit

Intraorbital Cancer

Glycogen-Rich Clear Cell Breast Carcinoma

Glycogen-Rich Carcinoma

Cerebellar Medulloblastoma

Papillary Adenoma

Glandular Papilloma

Adenoma

Rectum Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Rectum

Neuroendocrine Tumor Of The Rectum

Net Of The Rectum

Rectal Net

Rectal Neuroendocrine Tumor

Rectal Neuroendocrine Neoplasm

Cerebellopontine Angle Primitive Neuroectodermal Tumor

Cerebellopontine Angle Pnet

Gastric Gastrinoma

Gastric G-Cell Gastrin Producing Tumor

Gastric Gastrin-Producing Neuroendocrine Tumor

Large Cell Medulloblastoma

Pancreatic Cystadenoma

Cystadenoma Of Pancreas

Respiratory System Benign Neoplasm

Gallbladder Adenocarcinoma

Adenocarcinoma Of The Gallbladder

Carcinoma Of The Gallbladder

Vascular Cancer

Blood Vessel Tumors

Malignant Vascular Neoplasm

Renal Vein Leiomyosarcoma

Vascular Neoplasms

Blood Vessel Neoplasm

Blood Vessel Tumor

Blood Vessel Tumour Disorder

Haemangiomatous Tumour

Leiomyosarcoma Of The Renal Vein

Malignant Great Vessel Tumor

Malignant Tumor Of Pulmonary Artery

Malignant Tumor Of Pulmonary Vein

Malignant Vascular Tumor

Neoplasm Of Great Vessel

Pulmonary Artery Malignant Neoplasm

Pulmonary Vein Malignant Neoplasm

Vascular Tissue Neoplasm

Vascular Tumors

Blood Vessel Cancer

Neoplasms, Vascular Tissue

Malignant Neoplasm Of Great Vessels

Anaplastic Ependymoma

Ependymoma, Anaplastic

Undifferentiated Ependymoma

Neurohypophysis Granular Cell Tumor

Granular Cell Tumor Of The Neurohypophysis

Optic Nerve Astrocytoma

Astrocytic Tumor Of Optic Nerve

Optic Tract Astrocytoma

Visual Pathway Astrocytoma

Ovarian Cystic Teratoma

Papilledema

Choked Disk

Edema Of The Optic Disc

Myoblastoma

Benign Granular Cell Tumor

Vaginal Tubulovillous Adenoma

Pineal Region Teratoma

Teratoma Of Pineal Area

Horner'S Syndrome

Horner Syndrome

Bernard-Horner Syndrome

Oculosympathetic Palsy

Bernard Horner Syndrome

Cervical Sympathetic Paralysis

Von Passow Syndrome

Cervical Sympathetic Dystrophy

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Extraosseous Ewing'S Tumor

Extraosseous Ewing'S Tumour

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumour

Benign Ileal Neoplasm

Ileal Tumor

Ileal Neoplasms

Ileal Neoplasm

Thyroid Gland Medullary Carcinoma

Medullary Thyroid Carcinoma

Medullary Carcinoma Of The Thyroid Gland

Ultimobranchial Thyroid Tumor

Ultimobranchial Thyroid Tumour

Thyroid Cancer, Medullary

Amelanotic Melanoma

Melanoma, Amelanotic

Melanoma Amelanotic

Amelanotic Skin Melanoma

Cutaneous Ganglioneuroma

Ganglioneuroma Of Skin

Subungual Glomus Tumor

Subungual Glomus Tumour

Myxopapillary Ependymoma

Ependymoma Myxopapillary

Salpingitis Isthmica Nodosa

Adrenal Gland Disease

Adrenal Gland Diseases

Adrenal Gland Disorders

Papillary Thymic Adenocarcinoma

Papillary Carcinoma Of The Thymus

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Bile Duct Mucinous Adenocarcinoma

Mucinous Carcinoma Of The Bile Duct

Extrahepatic Bile Duct Mucinous Adenocarcinoma

Differentiating Neuroblastoma

Cardiovascular Organ Benign Neoplasm

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Pineal Region Choriocarcinoma

Pineal Choriocarcinoma

Skeletal Muscle Cancer

Malignant Tumor Of Skeletal Muscle

Skeletal Muscle Neoplasm

Obstructive Jaundice

Jaundice, Obstructive

Cholestatic Jaundice

Cholestatic Jaundice Syndrome

Obstructive Hyperbilirubinemia

Jaundice Obstructive

Jaundice Cholestatic

Orbital Disease

Orbit

Orbital Diseases

Endobronchial Lipoma

Exophthalmos

Proptosis

Vulva Basal Cell Carcinoma

Basal Cell Carcinoma Of Vulva

Basal Cell Carcinoma Of The Vulva

Neurilemmoma

Schwannoma

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Pineal Region Meningioma

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Hyperinsulinemic Hypoglycemia

Nesidioblastosis

Islet Cell Hyperplasia

Persistent Hyperinsulinemia Hypoglycemia Of Infancy

Hyperinsulinemic Hypoglycaemia

Suppression Of Tumorigenicity 12

Prostate Adenocarcinoma

Adenocarcinoma Of Prostate

ST12

Prostate Adenocarcinoma 1

Pac1

Low Grade Glioma

Benign Glioma

Parathyroid Adenoma

Adenoma Of Parathyroid

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Parathyroid Gland Adenoma

Frontal Lobe Neoplasm

Neoplasm Of Frontal Lobe

Malignant Neoplasm Of Frontal Lobe

Tumor Of Frontal Lobe

Thymus Sarcomatoid Carcinoma

Thymic Carcinosarcoma

Thymic Sarcomatoid Carcinoma

Multiple Endocrine Neoplasia, Type I

Multiple Endocrine Neoplasia Type 1

MEN1

Wermer Syndrome

Multiple Endocrine Neoplasia 1

Multiple Endocrine Neoplasia, Type 1

Men I

Endocrine Adenomatosis, Multiple

Mea I

Men Type I

Wermer'S Syndrome

Men1 Syndrome

Multiple Endocrine Adenomatosis

Endocrine Adenomatosis Multiple

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Eoe

Extraosseous Ewing Sarcoma

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Esft

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Pne

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Pnet Of The Chest Wall

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Disorder Of Eye

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WT1

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Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

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Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名稱

別名

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

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Synaptophysin Antibody

Synaptophysin Antibody?#4329

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Western blot analysis of extracts from rat brain, mouse brain and human cerebellum using Synaptophysin Antibody.

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Western blot analysis of extracts from rat brain, mouse brain and human cerebellum using Synaptophysin Antibody.

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Supporting Data

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Supporting Data

REACTIVITY

H M R

SENSITIVITY

Endogenous

MW (kDa)

38

SOURCE

Rabbit

Application Key:

WB-Western Blot

IP-Immunoprecipitation

IHC-Immunohistochemistry

ChIP-Chromatin Immunoprecipitation

C&R-CUT&RUN

C&T-CUT&Tag

DB-Dot Blot

eCLIP-eCLIP

IF-Immunofluorescence

F-Flow Cytometry

Species Cross-Reactivity Key:

H-Human

M-Mouse

R-Rat

Hm-Hamster

Mk-Monkey

Vir-Virus

Mi-Mink

C-Chicken

Dm-D. melanogaster

X-Xenopus

Z-Zebrafish

B-Bovine

Dg-Dog

Pg-Pig

Sc-S. cerevisiae

Ce-C. elegans

Hr-Horse

GP-Guinea Pig

Rab-Rabbit

All-All Species Expected

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Product Information

Product Usage Information

Application

Dilution

Western Blotting

1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 μg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Select your Protocol

Western Blotting

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Western Blotting Protocol

For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween? 20 at 4°C with gentle shaking, overnight.

NOTE: Please refer to primary antibody product webpage for recommended antibody dilution.

A. Solutions and Reagents

From sample preparation to detection, the reagents you need for your Western Blot are now in one convenient kit: #12957 Western Blotting Application Solutions Kit

NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.

20X Phosphate Buffered Saline (PBS): (#9808) To prepare 1 L 1X PBS: add 50 ml 20X PBS to 950 ml dH2O, mix.

10X Tris Buffered Saline (TBS): (#12498) To prepare 1 L 1X TBS: add 100 ml 10X to 900 ml dH2O, mix.

1X SDS Sample Buffer: Blue Loading Pack (#7722) or Red Loading Pack (#7723) Prepare fresh 3X reducing loading buffer by adding 1/10 volume 30X DTT to 1 volume of 3X SDS loading buffer. Dilute to 1X with dH2O.

10X Tris-Glycine SDS Running Buffer: (#4050) To prepare 1 L 1X running buffer: add 100 ml 10X running buffer to 900 ml dH2O, mix.

10X Tris-Glycine Transfer Buffer: (#12539) To prepare 1 L 1X Transfer Buffer: add 100 ml 10X Transfer Buffer to 200 ml methanol + 700 ml dH2O, mix.

10X Tris Buffered Saline with Tween? 20 (TBST): (#9997) To prepare 1 L 1X TBST: add 100 ml 10X TBST to 900 ml dH2O, mix.

Nonfat Dry Milk: (#9999).

Blocking Buffer: 1X TBST with 5% w/v nonfat dry milk; for 150 ml, add 7.5 g nonfat dry milk to 150 ml 1X TBST and mix well.

Wash Buffer: (#9997) 1X TBST.

Bovine Serum Albumin (BSA): (#9998).

Primary Antibody Dilution Buffer: 1X TBST with 5% BSA; for 20 ml, add 1.0 g BSA to 20 ml 1X TBST and mix well.

Biotinylated Protein Ladder Detection Pack: (#7727).

Blue Prestained Protein Marker, Broad Range (11-250 kDa): (#59329).

Blotting Membrane and Paper: (#12369) This protocol has been optimized for nitrocellulose membranes. Pore size 0.2 μm is generally recommended.

Secondary Antibody Conjugated to HRP: Anti-rabbit IgG, HRP-linked Antibody (#7074).

Detection Reagent: SignalFire? ECL Reagent (#6883).

B. Protein Blotting

A general protocol for sample preparation.

Treat cells by adding fresh media containing regulator for desired time.

Aspirate media from cultures; wash cells with 1X PBS; aspirate.

Lyse cells by adding 1X SDS sample buffer (100 μl per well of 6-well plate or 500 μl for a 10 cm diameter plate). Immediately scrape the cells off the plate and transfer the extract to a microcentrifuge tube. Keep on ice.

Sonicate for 10–15 sec to complete cell lysis and shear DNA (to reduce sample viscosity).

Heat a 20 μl sample to 95–100°C for 5 min; cool on ice.

Microcentrifuge for 5 min.

Load 20 μl onto SDS-PAGE gel (10 cm x 10 cm).

NOTE: Loading of prestained molecular weight markers (#59329, 10 μl/lane) to verify electrotransfer and biotinylated protein ladder (#7727, 10 μl/lane) to determine molecular weights are recommended.

Electrotransfer to nitrocellulose membrane (#12369).

C. Membrane Blocking and Antibody Incubations

NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.

I. Membrane Blocking

(Optional) After transfer, wash nitrocellulose membrane with 25 ml TBS for 5 min at room temperature.

Incubate membrane in 25 ml of blocking buffer for 1 hr at room temperature.

Wash three times for 5 min each with 15 ml of TBST.

II. Primary Antibody Incubation

Incubate membrane and primary antibody (at the appropriate dilution and diluent as recommended in the product webpage) in 10 ml primary antibody dilution buffer with gentle agitation overnight at 4°C.

Wash three times for 5 min each with 15 ml of TBST.

Incubate membrane with Anti-rabbit IgG, HRP-linked Antibody (#7074 at 1:2000) and anti-biotin, HRP-linked Antibody (#7075 at 1:1000–1:3000) to detect biotinylated protein markers in 10 ml of blocking buffer with gentle agitation for 1 hr at room temperature.

Wash three times for 5 min each with 15 ml of TBST.

Proceed with detection (Section D).

D. Detection of Proteins

Directions for Use:

Wash membrane-bound HRP (antibody conjugate) three times for 5 minutes in TBST.

Prepare 1X SignalFire? ECL Reagent (#6883) by diluting one part 2X Reagent A and one part 2X Reagent B (e.g. for 10 ml, add 5 ml Reagent A and 5 ml Reagent B). Mix well.

Incubate substrate with membrane for 1 minute, remove excess solution (membrane remains wet), wrap in plastic and expose to X-ray film.

* Avoid repeated exposure to skin.

posted June 2005

revised June 2020

Protocol Id: 10

Specificity / Sensitivity

Synaptophysin Antibody detects endogenous levels of total synaptophysin protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala230 of human synaptophysin. Antibodies are purified by peptide affinity chromatography.

Background

Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.

Valtorta, F. et al. (2004) Bioessays 26, 445-53.

Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.

Bonanomi, D. et al. (2007) Biochem J 404, 525-34.

Database Links

UniProt ID:

P08247

Entrez-Gene Id:

6855

View in PhosphoSitePlus?

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